Heart failure & cardiomyopathiesCohort study

Global Variations According to Sex in Patients Hospitalized for Heart Failure in the REPORT-HF Registry

JACC Heart FailPublication date not resolved

  • Prospective registry study
  • international
  • 44 countries

Authors' conclusion

Women were less likely to have diagnostic testing or receive guideline-directed care than men. A survival advantage for women was observed only in countries with low income disparity, suggesting that equity of HF care between sexes remains an unmet goal worldwide.

Study context

Population
Patients hospitalized for acute HF in 44 countries (REPORT-HF registry), stratified by country income level, income disparity and world region
Participants
18,553 patients · 44 countries
Exposure
Women vs men
  • Womenn = 7,181
  • Menn = 11,372reference
Outcome
All-cause mortality
Follow-up
1 year

Main finding

As reported in the abstract

1-year all-cause mortality (survival) by country income disparity

Advantage lost in countries with greater income disparity

Pinteraction < 0.001

Observational data: associations, not effects.

Further findings

Treatments that could worsen HF

P < 0.0001

Diagnostic testing and revascularization

Coronary angiography, cardiac stress tests and coronary revascularization less frequent in women than men
Women with acute heart failure (AHF) and reduced LVEF less likely to receive an implanted device, regardless of region or country income level

Original publication

Global Variations According to Sex in Patients Hospitalized for Heart Failure in the REPORT-HF Registry. JACC Heart Fail. doi:10.1016/j.jchf.2023.06.028

Summarised from the published abstract; every number is checked against it