Prevention & lipids

Greenspace visitation and risk of major adverse cardiovascular events: evidence from the Houston methodist cardiovascular learning health system registry

Eur J Prev CardiolPublished retrospective cohort study

Authors' conclusion

Mobility-derived greenspace visitation is associated with lower cardiovascular risk. These findings highlight greenspace engagement as a potentially modifiable behavioural exposure and support strategies to enhance access and utilization of greenspaces for cardiovascular prevention.

Study context

Population
Adults without baseline atherosclerotic cardiovascular disease in the Houston Methodist Cardiovascular Disease Learning Health System Registry (2016–2023)adults without baseline atherosclerotic cardiovascular disease
Participants
1,088,866 adults
Exposure
Greenspace visitation and incident major adverse cardiovascular events (MACE)
Outcome
Incident MACE:
  • Myocardial infarction
  • Stroke
  • Coronary revascularization
  • All-cause mortality

Main finding

As reported in the abstract

Incident MACE:
  • Myocardial infarction
  • Stroke
  • Coronary revascularization
  • All-cause mortality
Each additional 10 annual visitsHazard ratio, per 10 annual visits (95% CI)
Unadjusted; lower MACE risk
0.82(0.81–0.83)
Adjusted for demographics, comorbidities, and smoking; lower MACE risk
0.89(0.88–0.91)

Each additional 10 annual visits, as printed

Observational data: associations, not effects.

Further findings

Cohort characteristics

Median (SD) age
49 (17.6) years
Female
59.9%
Greenspace visitation varied across neighbourhoods and by demographic and socioeconomic characteristics

Dose-response of greenspace visitation and MACE (restricted cubic splines)

Non-linear relationship with risk reductions at low-to-moderate visitation, plateauing
10-15 visits annually

Event-free survival (Kaplan-Meier)

Higher event-free survival in high-visitation areas, consistent across MACE components

Original publication

Greenspace visitation and risk of major adverse cardiovascular events: evidence from the Houston methodist cardiovascular learning health system registry. Eur J Prev Cardiol. Published 19 October 2026. doi:10.1093/eurjpc/zwag470

Summarised from the published abstract; every number is checked against it

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