Heart failure & cardiomyopathies
Heart Failure Outcomes by Left Ventricular Ejection Fraction in a Contemporary Region-Wide Patient Cohort
Authors' conclusion
This study of contemporary patients with incident HF demonstrates that those with HFpEF and HFrEF differ considerably in terms of clinical presentation, prognosis, and care
Study context
- Population
- Patients with incident heart failure (HF) (first HF diagnosis 1 January 2015–31 December 2019) or prevalent HF (first HF diagnosis before 1 January 2020), Stockholm County, Sweden (CaReMe HF data)prevalent HF
- Participants
- 13,375 patients
- Exposure
- Incident HF subtypes by left ventricular ejection fraction (LVEF): HFrEF vs mildly reduced EF vs HFpEF
Methodological detailsregion-wide, Stockholm County, Sweden
- Region-wide
- Stockholm County, Sweden
Main finding
As reported in the abstract
- Prevalent HF: 39.2% women, mean age 73.9 years; multiple comorbidities (CVD, CKD, diabetes, cancer)
- Incident HF: 40.5% women, mean age 72.3 years; comorbidities already highly prevalent at first HF diagnosis
- Incident HFpEF received less specialist HF care at outpatient secondary care facilities than incident HFrEF
- HFrEF had higher risks of complications and higher healthcare burden (HF care and costs)
Observational data: associations, not effects.
Original publication
Heart Failure Outcomes by Left Ventricular Ejection Fraction in a Contemporary Region-Wide Patient Cohort. ESC Heart Fail. Published 4 February 2024. doi:10.
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