Heart failure & cardiomyopathies
Area-weighted unipolar voltage to predict heart failure outcomes in patients with ischaemic cardiomyopathy and ventricular tachycardia
Authors' conclusion
The newly proposed parameter awUV, easily available from routine voltage mapping, may be useful at identifying ICM patients at high risk for HFO.
Study context
- Population
- Patients with ischaemic cardiomyopathy referred for catheter ablation of ventricular tachycardia (VT)
- Participants
- 90 vs 60
- Comparison
- Low vs high area-weighted unipolar voltage (awUV)
- Derivationn = 90
- Validationn = 60
- Outcome
- Heart failure (HF)-related outcomes (HF death/LV assist device/heart transplant)
Methodological detailsconsecutive patients
- Consecutive patients
Performance
As reported in the abstract
awUV in patients with vs without HFO (derivation cohort) · median follow-up 45 months [IQR (34-83)]
HFO
4.51
IQR 3.69–5.31
No HFO
7.03
IQR 6.08–9.2
P < 0.001
- Reduced awUV (cut-off 5.58, ROC-determined) a strong predictor of HFO: 3-year HFO survival
- 97% vs. 57%
Further findings
Events in derivation cohort · median follow-up 45 months
- Died
- 36 (43%)
- HFO
- 23 (26%)
Validation of awUV cut-off: 2-year HFO-free survival
- Cut-off confirmed in validation cohort
- 96% vs. 60%
Original publication
Area-weighted unipolar voltage to predict heart failure outcomes in patients with ischaemic cardiomyopathy and ventricular tachycardia. Europace. Published 3 February 2024. doi:10.
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