Heart rate: an accessible risk indicator in adult congenital heart disease
Main finding · All-cause mortalityResult — go to the resultHazard ratio 1.57 95% CI 1.26–1.96Authors' conclusion
Higher heart rate is associated with lower survival and heart failure-free survival in ACHD.
Study context
- Population
- Patients with moderate or complex adult congenital heart disease at routine outpatient visit
- Participants
- 556 patients
- Exposure
- Higher vs lower resting heart rate
- Outcome
- All-cause mortality
- Follow-up
- Median 10.1 years
Methodological detailsobservational, Heart rate from resting 12-lead ECG (Modular ECG Analysis System (MEANS)); mean 69±13 bpm
- Observational
- Heart rate from resting 12-lead ECG (MEANS); mean 69±13 bpm
Main finding
As reported in the abstract
Hazard ratio
1.57
95% CI 1.26–1.96
Heart rate per 10 bpm
HR 1.57 (95% CI 1.26–1.96)
Per 10 bpm, as printed
- Deaths during follow-up
- 36 (6.5%)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | HR (95% CI) | |
|---|---|---|
| All-cause mortality or HFAdjusted | 1.33 (1.13–1.57) | |
| 0.512Hazard ratio (log scale) |
- All-cause mortality or HF — Reached secondary endpoint
- 83 (14.9%)
All-cause mortality or HF
- Higher heart rates had significantly lower HF-free survival
Original publication
Heart rate: an accessible risk indicator in adult congenital heart disease. Heart. Published 23 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →