Valvular & structural heart diseaseCross-sectional study
High Life’s Essential 8 score is associated with lower aortic valve calcification
- Cross-sectional study
Authors' conclusion
The study indicates that a higher LE8 score was associated with lower the presence of AVC.
Study context
- Population
- Kailuan cohort participants with health examination and contemporaneous ultrasoundKailuan cohort
- Participants
- 30,561 participants
- Exposure
- Moderate and high vs low LE8 CV health
- Outcome
- Presence of aortic valve calcification (AVC)
Main finding
As reported in the abstract
Presence of AVC
Odds ratio (95% CI)
Moderate CVHAVC reduced by 34%
0.66(0.60–0.72)
High CVHAVC reduced by 63%
0.37(0.27–0.50)
LE8 scorefor each standard deviation increase in the LE8 score; AVC decreased by 23%
0.77(0.74–0.80)
Each standard deviation increase in the LE8, as printed
- Detection rate of aortic valve calcification (AVC) significantly decreased with increased LE8 score
- P < 0.001
Observational data: associations, not effects.
Further findings
Individual LE8 components
- Diet, exercise, BMI, blood lipids, blood glucose and BP associated with reduced presence of AVC
- No impact of sleep and smoking on AVC presence
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
High Life’s Essential 8 score is associated with lower aortic valve calcification. Eur J Prev Cardiol. Published 13 May 2025. doi:10.1093/eurjpc/zwaf285
Summarised from the published abstract; every number is checked against it