Higher eicosapentaenoic acid levels and eicosapentaenoic acid/docosahexaenoic acid ratios are associated with lower cardiovascular mortality post-myocardial infarction
Authors' conclusion
Our study demonstrates that higher plasma levels of EPA and EPA/DHA ratio are associated with lower CV mortality one year after AMI.
Study context
- Population
- Patients hospitalised for acute MI
- Participants
- 572 patients
- Exposure
- Cardiovascular (CV) deaths vs survivors
- Outcome
- CV mortality
- Follow-up
- 1 year
Main finding
As reported in the abstract
Plasma FA levels by CV mortality · one-year follow-up
| Group | Eicosapentaenoic acid (EPA) | EPA/DHA ratio |
|---|---|---|
| Died | 0.47% (0.28-0.73) | 0.33 (0.22-0.43) |
Died
Eicosapentaenoic acid (EPA)0.47% (0.28-0.73)
EPA/DHA ratio0.33 (0.22-0.43)
- Lower EPA in those who died: 0.47% (0.28-0.73) vs. 0.73% (0.52-1.02)
- P < 0.001
- Lower EPA/DHA ratio in those who died: 0.33 (0.22-0.43) vs. 0.44 (0.33-0.61)
- P < 0.001
Observational data: associations, not effects.
Further findings
Inflammatory biomarkers (hs-CRP, interleukin-1β)
- More elevated in patients who died
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Higher eicosapentaenoic acid levels and eicosapentaenoic acid/docosahexaenoic acid ratios are associated with lower cardiovascular mortality post-myocardial infarction. Eur J Prev Cardiol. Published 14 October 2025. doi:10.
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