Aortic & peripheral vascular disease
Hospitalized upper extremity artery disease patients: treatment and long-term outcomes
Authors' conclusion
Upper extremity artery disease patients, irrespective of the underlying disease type, face a poor prognosis with elevated proportion of amputation and mortality. Male sex was linked to increased risk of future cardiovascular and limb events including death.
Study context
- Population
- Patients hospitalised with a primary diagnosis of upper extremity artery disease (UEAD), Germany, 2010–201743% female
- Participants
- 2,437 patients
- Exposure
- Men vs women
- Outcome
- Prevalence, treatment patterns, and short- and long-term outcomes (mortality, amputation), with focus on sex-related disparities
- Follow-up
- Median 5.5 years
Methodological detailshealth claims data, 11 statutory health insurance funds (AOK)
- Health claims data
- 11 statutory health insurance funds (AOK)
Main finding
As reported in the abstract
5-year mortality, entire population
almost 50%
Observational data: associations, not effects.
Further findings
Revascularisation at index stay
Disease type
- Solely atherosclerotic (UEADa)
- 80%
- Concomitant inflammatory/connective tissue disease (UEADc/i)
- 20%
Comorbidities
- Coronary, cerebrovascular and lower extremity artery disease, CKD and HF more frequent in men than women
Safety
Upper limb amputation · UEADa · despite equal secondary preventive pharmacotherapy
P < 0.001
Upper limb amputation · UEADc/i · despite equal secondary preventive pharmacotherapy
P < 0.01
Original publication
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