Immediate versus staged complete revascularisation in patients presenting with ST-elevation myocardial infarction (STEMI) and multivessel disease
Primary resultResult — go to the resultHazard ratio 0.84 95% CI 0.47–1.50Authors' conclusion
Clinical outcomes at 1 year were similar for STEMI patients who had undergone ICR and those who had undergone SCR.
Study context
- Population
- Patients presenting with STEMI and multivessel disease
- Participants
- 608 patients
- Comparison
- Immediate vs staged complete revascularisation
- Immediate complete revascularisation (ICR)n = 305
- Staged complete revascularisation (SCR)n = 303reference
- Primary endpoint
- Composite of:
- All-cause mortality
- MI
- Any unplanned ischaemia-driven revascularisation
- Cerebrovascular events
- Follow-up
- 1 year post-index procedure
Methodological detailsprespecified analysis, Enrolment June 2018 to October 2021
- Prespecified analysis
- Enrolment June 2018 to October 2021
Primary result
As reported in the abstract
1 year
Hazard ratio
0.84
95% CI 0.47–1.50
P = 0.55
By group
ICR vs SCR
HR 0.84 (95% CI 0.47–1.50); P = 0.55
Further findings
| Outcome | ICR | SCR | HR (95% CI) | P value | |
|---|---|---|---|---|---|
| All-cause mortality · 1 year | 2.3% | 1.3% | 1.77 (0.52–6.04) | P = 0.36 | |
| MI · 1 year | 1.7% | 3.3% | 0.50 (0.17–1.47) | P = 0.21 | |
| Unplanned ischaemia-driven revascularisation · 1 year | 4.1% | 5.0% | 0.80 (0.38–1.71) | P = 0.57 | |
| Cerebrovascular events · 1 year | 1.4% | 1.3% | 1.01 (0.25–4.03) | P = 0.99 | |
| Primary endpoint · 30 daysTrend towards reduction | 3.0% | 6.0% | 0.50 (0.22–1.11) | P = 0.09 | |
| 0.10.31310Hazard ratio (log scale) |
Overall hospital stay
P < 0.001
Original publication
Immediate versus staged complete revascularisation in patients presenting with STEMI and multivessel disease. EuroIntervention. Published 15 July 2024. doi:10.
Summarised from the published abstract; every number is checked against it