Heart failure & cardiomyopathies
Impact of Left Ventricular Ejection Fraction Phenotypes on Healthcare Resource Utilization in Hospitalized Heart Failure: A Secondary Analysis of REPORT-HF
Authors' conclusion
In patients hospitalized for HF, overall HCRU was similarly high across LVEF spectrum, reflecting the subtle clinical differences among LVEF phenotypes during hospitalization.
Study context
- Population
- Patients hospitalized for heart failure (HF) in a worldwide registry
- Participants
- 16,943 patients
- Comparison
- HFmrEF and HFpEF vs HFrEF
- Primary endpoint
- Healthcare resource utilization (HCRU) by left ventricular ejection fraction (LVEF) phenotype
Methodological detailsworldwide registry
- Worldwide registry
Primary result
As reported in the abstract
HCRU
≥2 in- and out-of-hospital services
ICU
Further findings
Prevalence of LVEF phenotypes
HF hospitalization · 12 months
| Outcome | Adjusted HR (95% CI) | |
|---|---|---|
| All-cause and CV mortality · 12 monthsHFmrEFvs HFrEFCV mortality | 0.80 (0.70–0.92) | |
| All-cause and CV mortality · 12 monthsHFpEFvs HFrEFAll-cause mortality | 0.64 (0.59–0.87) | |
| All-cause and CV mortality · 12 monthsHFpEFvs HFrEFCV mortality | 0.63 (0.56–0.71) | |
| 0.512Adjusted hazard ratio (log scale) |
| Outcome | HFrEF | HFmrEF | HFpEF | Adjusted HR (95% CI) |
|---|---|---|---|---|
| Discharge beta-blocker prescription | — not stated in the abstract | 74% | 67% | |
| All-cause and CV mortality · 12 monthsHFmrEF vs HFrEF · all-cause mortality | 0.78 (0.59–0.71) |
— not stated in the abstract
Discharge beta-blocker prescription
- Neurohormonal inhibitor prescription in HFrEF <80% for each agent
In-hospital mortality, 12-month non-CV mortality, 12-month all-cause hospitalization
- Similar among groups
Original publication
Impact of Left Ventricular Ejection Fraction Phenotypes on Healthcare Resource Utilization in Hospitalized Heart Failure: A Secondary Analysis of REPORT-HF. Eur J Heart Fail. Published 12 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →