Valvular & structural heart disease
Impact of Balloon Postdilation on Long-Term Bioprosthesis Durability After TAVR
Main findingResult — go to the resultSubdistribution hazard ratio 0.37 95% CI 0.15–0.95Authors' conclusion
BPD was associated with a lower incidence of stage 2 and 3 hemodynamic valve deterioration and bioprosthetic valve failure, along with improved bioprosthetic valve hemodynamic parameters over time.
Study context
- Population
- Consecutive patients undergoing TAVR (May 2007–March 2024) alive at 1 year and without valve-in-valve procedurematched cohort
- Participants
- 1,911 patients
- Exposure
- Balloon postdilation (BPD) vs no BPD during TAVR
- BPDn = 215
- No-BPDn = 761reference
- Outcome
- Stage 2 or 3 hemodynamic valve deterioration (VARC-3)
Methodological detailssingle-centre, propensity-score matched
- Single-centre
- Propensity-score matched
Main finding
As reported in the abstract
Subdistribution hazard ratio
0.37
95% CI 0.15–0.95
P = 0.039
By group
BPDvs No-BPD
subdistribution HR 0.37 (95% CI 0.15–0.95); P = 0.039
Observational data: associations, not effects.
Further findings
| Outcome | No-BPD | Subdistribution HR (95% CI) | P value | |
|---|---|---|---|---|
| Bioprosthetic valve failure | 5.1% | 0.39 (0.15–0.98) | P = 0.046 | |
| 0.10.31310Subdistribution hazard ratio (log scale) |
Echocardiographic hemodynamic parameters · up to 10 years
- Better hemodynamic parameters over time with BPD
HF hospitalization
- Trend toward higher prevalence with BPD
Original publication
Impact of Balloon Postdilation on Long-Term Bioprosthesis Durability After TAVR. Circ Cardiovasc Interv. Published 28 October 2025. doi:10.
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