Arrhythmias & electrophysiology

Impact of Catheter Ablation of Electrical Storm on Survival: A Propensity Score-Matched Analysis

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

In propensity-matched analyses, this large study shows that CA-based management of patients admitted for ES is associated with a reduction in mortality compared with medical treatment, particularly in patients with a low ejection fraction.

Study context

Population
Consecutive patients admitted for electrical stormmatched 1:1, 2 groups of 288
Participants
780 patients
Exposure
Catheter ablation vs medical therapy alone
  • Catheter ablation (CA)n = 288
  • Medical therapy alonen = 288reference
Outcome
Survival after discharge
Follow-up
1 year
Methodological detailspropensity-score matched, multicentre, 4 tertiary centres
  • Propensity-score matched
  • Multicentre
  • 4 tertiary centres

Main finding

As reported in the abstract

P < 0.001

Observational data: associations, not effects.

Further findings

Survival after discharge · 3 years

P = 0.017

ES recurrence · 1 year

P < 0.001

OutcomeHR (95% CI)
Effect of ablation, by subgroup (age >70 y; LVEF <35%)Age >70 years0.39 (0.24–0.66)
Effect of ablation, by subgroup (age >70 y; LVEF <35%)LVEF <35%0.39 (0.27–0.59)

Original publication

Impact of Catheter Ablation of Electrical Storm on Survival: A Propensity Score-Matched Analysis. JACC Clin Electrophysiol. Published 31 July 2024. doi:10.1016/j.jacep.2024.05.032

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