Arrhythmias & electrophysiology

Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design

Am Heart JPublished multicenter, double-blinded, randomized trial

Study context

Population
Patients admitted to an intensive care unit with electrical storm (ES)planned enrolment (will be randomized)
Participants
192 patients
Planned comparison
Dexmedetomidine to placebo in the acute treatment of patients with ES
Primary endpoint
composite of:
  • All-cause in-hospital mortality
  • Recurrent ventricular arrhythmia prompting intervention
Follow-up
Duration of hospitalization
Methodological detailsrandomized in a 1:1 fashion, rationale and design
  • Randomized in a 1:1 fashion
  • Rationale and design

No results yet. This paper sets out the design of a trial; its results are to come.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Study evaluating dexmedetomidine in the acute treatment of electrical storm (SEDATE): Rationale and design. Am Heart J. Published 25 January 2026. doi:10.1016/j.ahj.2026.107358

Composed by AI from the published abstract and checked against it. How Briefs are made →

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