Arrhythmias & electrophysiology
Impact of Catheter Ablation on Cognitive Function in Atrial Fibrillation: A Randomized Control Trial
Authors' conclusion
POCD was observed following AF ablation. However, this was transient with complete recovery at 12-month follow-up.
Study context
- Population
- Patients with symptomatic atrial fibrillation (AF) who failed at least 1 antiarrhythmic drug96 completed
- Participants
- 100 patients
- Comparison
- AF catheter ablation vs ongoing medical therapy
- Primary endpoint
- Persistent new cognitive dysfunction (6 cognitive tests)
- Follow-up
- 12 months
Methodological detailsprospective
- Prospective
Primary result
As reported in the abstract
New cognitive dysfunction
P = NS
Further findings
| Outcome | Ablation | Medical | P value |
|---|---|---|---|
| New cognitive dysfunction · 3 months | 14% | — not stated in the abstract | P = 0.03 |
| New cognitive dysfunction · 6 months | 4% | — not stated in the abstract | P = NS |
| Significant improvement in cognitive scores · 12 months | 14% | 0 events | P = 0.007 |
— not stated in the abstract
Predictor of postoperative cognitive dysfunction (POCD)
- Ablation time an independent predictor of POCD
- P = 0.03
Original publication
Impact of Catheter Ablation on Cognitive Function in Atrial Fibrillation: A Randomized Control Trial. JACC Clin Electrophysiol. Published 24 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →