Arrhythmias & electrophysiology
Impact of Colchicine Monotherapy on the Risk of Acute Pericarditis Following Atrial Fibrillation Ablation
Authors' conclusion
Colchicine therapy starting 7 days before to 1 month after the ablation procedure was associated with significantly lower risk of acute pericarditis and related hospitalization.
Study context
- Population
- Consecutive atrial fibrillation (AF) patients undergoing first catheter ablation
- Participants
- 1,075 patients
- Exposure
- Colchicine vs no colchicine
- Group 1n = 607reference
- Group 2n = 213
- Group 3n = 255
- Outcome
- Acute pericarditis
Methodological detailsconsecutive patients, 1-year follow-up
- Consecutive patients
- 1-year follow-up
Main finding
As reported in the abstract
Acute pericarditis symptoms
P < 0.001
- Overall acute pericarditis
- 129 patients (12%)
Observational data: associations, not effects.
Further findings
Mild-moderate and severe pericarditis
- Significantly lower in Group 2
Arrhythmia-free survival, paroxysmal AF (subgroup) · 1 year
- Significantly higher with colchicine vs no colchicine
Original publication
Impact of Colchicine Monotherapy on the Risk of Acute Pericarditis Following Atrial Fibrillation Ablation. JACC Clin Electrophysiol. Published 19 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →