Congenital heart diseaseCross-sectional study
Impact of congenital heart disease on personality disorders in adulthood
- Cross-sectional study
Authors' conclusion
Personality disorders, particularly borderline- and cluster C, are significantly more frequent in ACHD compared to GP and associated with depression, anxiety, and decreased QOL.
Study context
- Population
- Adults with congenital heart disease
- Participants
- 210 adults
- Exposure
- Adults with congenital heart disease (ACHD) vs general population
- ACHDn = 210
- Outcome
- PD point prevalence (SCID-II)
Main finding
As reported in the abstract
PD prevalence
PD prevalence
Borderline PD
Cluster C PD
Observational data: associations, not effects.
Further findings
Factors associated with PD diagnosis
- Surgery age ≤12 years (χ²(1) = 7.861, ϕ = 0.195)
- P = 0.005
- Higher childhood trauma levels (U = 2583.5, Z = −3.585)
- P < 0.001
Anxiety, depression and QOL in ACHD with vs without PD
- Higher anxiety with PD (HADS-A: U = 2116.0, Z = −5.723)
- P < 0.001
- Higher depression with PD (HADS-D: U = 2254.5, Z = −5.392)
- P < 0.001
- Higher depression with PD (MADRS: U = 2645.0, Z = −4.554)
- P < 0.001
- Lower QOL with PD (U = 2538.5, Z = −4.723)
- P < 0.001
Original publication
Impact of congenital heart disease on personality disorders in adulthood. Eur J Prev Cardiol. Published 24 January 2024. doi:10.1093/eurjpc/zwae030
Summarised from the published abstract; every number is checked against it