Valvular & structural heart disease
Impact of extra-mitral valve cardiac involvement in patients with primary mitral regurgitation undergoing transcatheter edge-to-edge repair
Authors' conclusion
Grading cardiac involvement may help refine risk stratification, since at least 1 group of extra-MV cardiac involvement represents in itself a negative predictor of midterm outcome.
Study context
- Population
- Patients with primary mitral regurgitation undergoing transcatheter edge-to-edge repair (TEER), Italian GIOTTO registry
- Participants
- 654 patients
- Exposure
- Extra-MV cardiac involvement vs no cardiac involvement
- NIn = 58reference
- Left heart involvement (LHI)n = 343
- Right heart involvement (RHI)n = 253
- Outcome
- All-cause death
- Follow-up
- 2-year follow-up
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Survival (Kaplan-Meier)
- Significantly worse survival with LHI and RHI
- p=0.041
Observational data: associations, not effects.
Further findings
- Acute technical success, all patients
- 98%
Original publication
Impact of extra-mitral valve cardiac involvement in patients with primary mitral regurgitation undergoing transcatheter edge-to-edge repair. EuroIntervention. Published 18 December 2023. doi:10.
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