Acute cardiac care & resuscitation

Impact of Female Sex on Cardiogenic Shock Outcomes: A Cardiogenic Shock Working Group Report

JACC Heart FailPublished Retrospective cohort study

Authors' conclusion

Women with HF-CS had worse outcomes and more vascular complications than men with HF-CS.

Study context

Population
Patients with cardiogenic shock (AMI-CS or HF-CS) in the Cardiogenic Shock Working Group
Participants
5,083 patients
Exposure
Women vs men with cardiogenic shock
  • Womenn = 1,522
Outcome
Survival at discharge
Follow-up
Discharge
Methodological detailspropensity-score matched
  • Propensity-score matched

Main finding

As reported in the abstract

Survival at discharge, HF-CS (before PSM)

P = 0.009

Observational data: associations, not effects.

Further findings

AMI-CS

P = 0.03

De novo HF-CS

P < 0.001

Maximum SCAI stage E, HF-CS (before PSM)

P = 0.04

Pulmonary artery catheterization

P < 0.001

Heart transplantation

P < 0.001

LV assist device implantation

P = 0.01

Safety

Vascular complications (all CS etiologies)

P < 0.001

Bleeding

P = 0.01

Limb ischemia

P = 0.001

Vascular complications after PSM · matched cohort

P = 0.06

Original publication

Impact of Female Sex on Cardiogenic Shock Outcomes: A Cardiogenic Shock Working Group Report. JACC Heart Fail. Published 6 November 2023. doi:10.1016/j.jchf.2023.09.025

Composed by AI from the published abstract and checked against it. How Briefs are made →

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