Valvular & structural heart disease

Impact of Optimal Procedural Result After Transcatheter Edge-to-Edge Tricuspid Valve Repair: Results From TRI-SPA Registry

JACC Cardiovasc IntervPublished Multicentre registry study

Main findingResult — go to the resultHazard ratio 2.277

Authors' conclusion

An optimal procedural result after TEER might be associated with improved outcomes.

Study context

Population
Patients undergoing tricuspid transcatheter edge-to-edge repair (TEER) in 15 Spanish centres, June 2020–May 2023
Participants
280 patients
Exposure
Residual tricuspid regurgitation (TR) 0/1+ vs 2+ vs ≥3+ after tricuspid TEER
  • TR 0/1+n = 120reference
  • TR 2+n = 111
  • TR ≥3+n = 49
Outcome
Composite of:
  • All-cause death
  • HF hospitalisation
  • Tricuspid reintervention
Follow-up
1 year
Methodological details15 Spanish centres
  • 15 Spanish centres

Main finding

As reported in the abstract

Hazard ratio

2.277

P = 0.044

By group

Observational data: associations, not effects.

Secondary outcomes

NYHA class I or II and sustained TR reduction

Higher rates in TR 0/1+
P < 0.001

Predictors of achieving TR 0/1+

Small coaptation gap and absence of septal leaflet tethering were independent predictors

Original publication

Impact of Optimal Procedural Result After Transcatheter Edge-to-Edge Tricuspid Valve Repair: Results From TRI-SPA Registry. JACC Cardiovasc Interv. Published 6 November 2024. doi:10.1016/j.jcin.2024.08.003

Summarised from the published abstract; every number is checked against it

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