Valvular & structural heart disease
Transcatheter Mitral Valve Replacement Using Annular Reduction by Cinching With Transcatheter Edge-to-edge Repair (TEER) in the Commissure (ARCTIC)
Authors' conclusion
In patients with large annuli and sufficient annular calcium, a hybrid mitral TEER and valve replacement with the SAPIEN platform can be successfully used to facilitate transcatheter mitral valve replacement.
Study context
- Population
- Mitral annular calcification with valve dysfunction, long intercommissural distance and large annulus area, high perceived risk of valve embolization, no surgical or trial-based TMVR device available
- Participants
- 13 participants
- Outcome
- Procedural success
Methodological detailsinitial experience
- Initial experience
Main finding
As reported in the abstract
Valve implantation successful
12 of 13 patients
NTW device size used
10 of 13 instances
Observational data: associations, not effects.
Further findings
Baseline annular anatomy
- Median intercommissural distance
- 39.1 mm
- Median annular area
- 930 mm²
Safety
- Frank valve embolization into the left atrium
- 1 case
- Paravalvular leak among the 12 successful cases
- 1+ or less
- No paravalvular leak adjacent to the TEER device
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Transcatheter Mitral Valve Replacement Using Annular Reduction by Cinching With TEER in the Commissure (ARCTIC). Circ Cardiovasc Interv. Published 6 November 2024. doi:10.
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