Valvular & structural heart diseaseCohort study
Impact of Proportionality of Secondary Tricuspid Regurgitation on Outcomes After Tricuspid Transcatheter Edge-to-Edge Repair
- registry
- International Multisite
Authors' conclusion
The conceptual framework of proportionality is applicable to TR with EROA/RVEDD, defining a higher risk RV-dominant phenotype with a trend towards worse survival after tricuspid transcatheter edge-to-edge repair.
Study context
- Population
- Patients undergoing tricuspid transcatheter edge-to-edge repair from the TRIVALVE registrypatients included · right ventricular (RV) dominant 67 · RV-TR codominant 68 · tricuspid regurgitation (TR) dominant 69
- Participants
- 204 patients
- Exposure
- Tertiles of the ratio between effective regurgitant orifice area (EROA) and RVEDD
- RV dominantn = 67
- RV-TR codominantn = 68
- TR dominantn = 69
- Outcome
- All-cause mortality
- Follow-up
- Median 9.7 months (4.2-12.0)
Main finding
As reported in the abstract
- Trend towards worse prognosis for the RV-dominant group, as compared with the RV-TR codominant and TR dominant groups
Observational data: associations, not effects.
Further findings
Baseline characteristics
- The 3 groups presented different baseline characteristics
Original publication
Impact of Proportionality of Secondary Tricuspid Regurgitation on Outcomes After Tricuspid Transcatheter Edge-to-Edge Repair. Circ Cardiovasc Interv. Published 26 March 2026. doi:10.1161/circinterventions.125.016269
Summarised from the published abstract; every number is checked against it