Valvular & structural heart disease
Impact of Residual Mitral Regurgitation and Gradient After M‑TEER: 1‑Year Outcomes From the CLASP IID Trial
Authors' conclusion
In the CLASP IID trial, an optimal result was associated with improved hemodynamics with significantly higher freedom from MAEs, all-cause mortality, and composite events at 1 year.
Study context
- Population
- Patients undergoing mitral transcatheter edge-to-edge repair (M-TEER) in the CLASP IID trial with available discharge echocardiogramwith discharge echocardiogram
- Participants
- 284 patients
- Comparison
- Optimal vs suboptimal discharge result after M-TEER
- Optimal resultn = 206
- Suboptimal resultn = 78reference
Primary result
As reported in the abstract
Freedom from clinical events · 1 year
Freedom from MAEs
P = 0.023
Freedom from mortality
Freedom from mortality, HF hospitalization or reintervention
- Optimal result vs Suboptimal result: P = 0.016 — freedom from mortality
- Optimal result vs Suboptimal result: P = 0.022 — freedom from composite
Further findings
Freedom from clinical events within suboptimal result: MR ≤1+ and MVG >5 mm Hg vs MR ≥2+ and MVG ≤5 mm Hg (subgroup) · 1 year
Freedom from MAEs
Freedom from mortality
Freedom from composite
Original publication
Impact of Residual Mitral Regurgitation and Gradient After M‑TEER: 1‑Year Outcomes From the CLASP IID Trial. JACC Cardiovasc Imaging. Published 3 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →