Acute cardiac care & resuscitation
Impact of right heart failure in patients with cardiogenic shock
- Retrospective analysis of the Vizient® Clinical Database
- inverse probability of treatment weighting (IPTW)
+1 more
- inverse probability of treatment weighting (IPTW)
Authors' conclusion
The presence of RHF is associated with increased in-hospital mortality in patients admitted with CS.
Study context
- Population
- Adults ≥18 years old admitted 1 October 2015 to 30 June 2023 with a diagnosis of cardiogenic shock (CS)patients with CS, including 11.3% (n = 39,610) with right heart failure (RHF)
- Participants
- 348,919 adults
- Exposure
- In-hospital mortality between patients with and without a diagnosis of RHF as well as by SCAI shock stages B through E
- RHFn = 39,610
Main finding
As reported in the abstract
Age
RHF
60.5
non-RHF CS
65.5
Observational data: associations, not effects.
Further findings
HF as primary admission diagnosis
AMI as primary admission diagnosis
Out-of-hospital cardiac arrest
| Outcome | absolute mortality increase (95% CI) | P value | |
|---|---|---|---|
| In-hospital mortality · After adjustment | 2.4% (1.9–2.9%) | P < 0.001 | |
| −2024Difference (linear scale) |
- Heart failure (HF) as primary admission diagnosis: P < 0.001
- Acute myocardial infarction (AMI) as primary admission diagnosis: P < 0.001
- Out-of-hospital cardiac arrest: P < 0.001
- In-hospital mortality: increase with RHF; after adjustment (IPTW); also when stratified by SCAI shock stage
HF as primary admission diagnosis
- Patients with RHF presented in earlier SCAI shock stages
In-hospital mortality, isolated RHF
- Higher absolute in-hospital mortality with isolated RHF
- 9.8%; 95% (CI): 8.6-11.0%; P < 0.001
Original publication
Impact of right heart failure in patients with cardiogenic shock. Eur Heart J Acute Cardiovasc Care. Published 21 March 2026. doi:10.1093/ehjacc/zuag041
Summarised from the published abstract; every number is checked against it