Heart failure & cardiomyopathies

Implantable Hemodynamic Monitors Improve Survival in Patients With Heart Failure and Reduced Ejection Fraction

J Am Coll CardiolPublished Patient-level pooled meta-analysis of randomised trials

Pooled resultResult — go to the resultHazard ratio 0.75 95% CI 0.57–0.99

Authors' conclusion

Management of patients with HFrEF using an implantable hemodynamic monitor significantly reduces both mortality and HF hospitalizations. The reduction in HF hospitalizations is seen early in the first year of monitoring and mortality benefits occur after the first year.

Study context

Population
Patients with heart failure and reduced ejection fraction (HFrEF)
Participants
1,350 patients3 RCTs
Comparison
Hemodynamic-monitoring guided management vs control
Outcome
All-cause mortality and heart failure (HF) hospitalizations

Pooled result

As reported in the abstract

Hazard ratio

0.75

95% CI 0.57–0.99

P = 0.043

Hemodynamic-monitoring guided managementvs control
HR 0.75 (95% CI 0.57–0.99); P = 0.043

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Implantable Hemodynamic Monitors Improve Survival in Patients With Heart Failure and Reduced Ejection Fraction. J Am Coll Cardiol. Published 13 February 2024. doi:10.1016/j.jacc.2023.11.030

Composed by AI from the published abstract and checked against it. How Briefs are made →

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