Heart failure & cardiomyopathies

In Heart Failure, Echocardiographic Parameters of Right Ventricular Function are Powerful Tools to Predict Renal Failure

ESC Heart FailPublished retrospective cohort study

Authors' conclusion

The results of this work support the theory of right-sided cardiac backward failure, often accompanied by hypervolaemia, as a leading cause of HF-related renal failure. Right heart parameters, especially TR, TAPSE and IVC, are obtained easily by transthoracic echocardiography and can predict renal failure.

Study context

Population
Patients with heart failure examined at regular intervals at an outpatient clinic for heart failure (HF)consecutive patients with HF
Participants
281 patients
Outcome
Right ventricular dysfunction and CKD and WRF
Methodological detailsconsecutive patients, outpatient clinic for HF
  • Consecutive patients
  • Outpatient clinic for HF

Main finding

As reported in the abstract

  • Right ventricular dysfunction was associated with chronic kidney disease (CKD) and worsening renal function (WRF)

Observational data: associations, not effects.

Further findings

Echocardiographic parameters and renal failure

ORP value
TAPSE < 15 mmCorrelated with renal failure2.932P < 0.001
TR > I°Correlated with renal failure5.958P < 0.001
Dilatation of IVCCorrelated with renal failure3.670P < 0.001
OutcomeORP value
N-terminal pro-B-type natriuretic peptide levels and CKDAssociated with CKD6.109P < 0.001

N-terminal pro-B-type natriuretic peptide levels and CKD

N-terminal pro-B-type natriuretic peptide levels correlated with pressure and volume load of the right heart

Original publication

In Heart Failure, Echocardiographic Parameters of Right Ventricular Function are Powerful Tools to Predict Renal Failure. ESC Heart Fail. Published 25 February 2025. doi:10.1002/ehf2.15176

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