Coronary disease & ACS

In vivo predictors of plaque erosion in patients with ST-segment elevation myocardial infarction: a clinical, angiographical, and intravascular optical coherence tomography study

Eur Heart JPublished Prospective cohort study

Authors' conclusion

Plaque erosion was a predictable clinical entity distinct from plaque rupture in STEMI patients

Study context

Population
STEMI patients undergoing pre-intervention optical coherence tomography
Participants
822 patients
Exposure
Plaque erosion vs plaque rupture
  • Plaque erosionn = 209
  • Plaque rupturen = 564reference
Outcome
In vivo predictors of plaque erosion
Methodological detailsprospective series, OCT imaging
  • Prospective series
  • OCT imaging

Main finding

As reported in the abstract

Predictors of plaque erosion (multivariable analysis)

Predictors of plaque erosion (multivariable analysis)

LAD location

Right coronary artery location Plaque rupture 43.3%

Erosion more frequent in women <50 vs ≥50 years
P = 0.009
Similar, less striking trend in men
P = 0.011
Erosion more frequent near a bifurcation
P < 0.001

Observational data: associations, not effects.

Original publication

In vivo predictors of plaque erosion in patients with ST-segment elevation myocardial infarction: a clinical, angiographical, and intravascular optical coherence tomography study. Eur Heart J. Published 13 March 2018. doi:10.1093/eurheartj/ehy101

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