Heart failure & cardiomyopathies

Incidence of Clinical Outcomes in Heart Failure Patients with and Without Advanced Chronic Kidney Disease

ESC Heart FailPublished Retrospective cohort study

Authors' conclusion

Patients with advanced CKD had a higher incidence of mortality and poorer kidney outcomes than those without advanced CKD, but a similar incidence of HF hospitalizations.

Study context

Population
Heart failure (HF) patients identified from nationwide registries, 2014 to 2018 (median age 73.9 years)
Participants
21,959 patients
Exposure
HF patients by baseline estimated glomerular filtration rate (eGFR): eGFR < 30 vs 60 > eGFR ≥ 30 vs eGFR ≥ 60
Outcome
All-cause mortality, HF hospitalization, end-stage kidney disease and sustained 50% eGFR decline (cumulative incidence functions)
Follow-up
4 year
Methodological detailsnationwide registries
  • Nationwide registries

Main finding

As reported in the abstract

All-cause mortality

HF hospitalization

Kidney outcome as first event

Observational data: associations, not effects.

Original publication

Incidence of Clinical Outcomes in Heart Failure Patients with and Without Advanced Chronic Kidney Disease. ESC Heart Fail. Published 8 July 2024. doi:10.1002/ehf2.14933

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