Acute cardiac care & resuscitation
Increased rate of anoxic brain damage with laryngeal tube compared to endotracheal intubation in patients with shockable out-of-hospital cardiac arrest – Experience from the HAnnover COoling REgistry (HACORE)
Authors' conclusion
In this cohort, use of LT was associated with a higher rate of anoxic brain damage and worse functional neurological outcome compared to use of ETI.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) patients with shockable rhythms and return of spontaneous circulation before transport, treated per the Hannover Cardiac Resuscitation Algorithm incl. therapeutic hypothermia (HACORE)
- Participants
- 452 patients
- Exposure
- Laryngeal tube (LT) vs endotracheal intubation (ETI) for primary airway management
- LTn = 47
- ETIn = 405reference
- Outcome
- Anoxic brain damage
Methodological detailsreal-world registry
- Real-world registry
Main finding
As reported in the abstract
P = 0.011
Observational data: associations, not effects.
Further findings
Mortality
P = 0.487
Good neurological outcome (CPC 1&2) in survivors
P = 0.013
Safety
Pneumonia
P < 0.001
Original publication
Increased rate of anoxic brain damage with laryngeal tube compared to endotracheal intubation in patients with shockable out-of-hospital cardiac arrest – Experience from the HAnnover COoling REgistry (HACORE). Resuscitation. Published 20 October 2024. doi:10. 1016/ j. resuscitation. 2024. 110416
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