Cardio-oncology & other

Infective endocarditis and the association to income as a proxy for socioeconomic position: A Danish nationwide register-based cohort study

Am Heart JPublished Danish nationwide register-based cohort study

Main finding · Infective endocarditisResult — go to the resultIncidence rate ratio 1.58 CI 1.43–1.75

Authors' conclusion

In a nationwide population, a significant association between low income and increasing incidence of infective endocarditis was observed. The association was most evident in younger individuals.

Study context

Population
All Danish residents above 30 years of age, January 1, 2007 through December 31, 2017individuals (median age = 47 years), median follow-up of 11 years
Participants
3,524,314 participants
Exposure
Lowest vs highest income group
Outcome
Infective endocarditis
Follow-up
Median 11 years
Methodological detailstime-updated estimates of disposable income, multivariate Poisson Regression analyses
  • Time-updated estimates of disposable income
  • Multivariate Poisson Regression analyses

Main finding

As reported in the abstract

Incidence rate ratio

1.58

CI 1.43–1.75

Lowest income group vs highest income group
IRR 1.58 (CI 1.43–1.75)
Declining level of income was associated with increasing incidence rates of infective endocarditis, spanning from 7 to 20 events/100,000 person-years
7 to 20 events/100,000 person-years

Observational data: associations, not effects.

Further findings

The association between decreasing income and increasing IRR of infective endocarditis was present across all age groups, although the association was strongest in the young population

Original publication

Infective endocarditis and the association to income as a proxy for socioeconomic position: A Danish nationwide register-based cohort study. Am Heart J. Published 5 April 2025. doi:10.1016/j.ahj.2025.04.003

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