Arrhythmias & electrophysiology
Initial Experience With Intercostal Insertion of an Extravascular Implantable Cardioverter Defibrillator (ICD) Lead Compatible With Existing Pulse Generators
Authors' conclusion
This first-in-human study documented the safe and reliable placement of a novel extravascular ICD lead with effective sensing and defibrillation of induced ventricular fibrillation using commercial DF-4 ICD PGs.
Study context
- Population
- De novo or replacement transvenous ICD patients receiving a concomitant extravascular ICD lead inserted intercostally along the left parasternal margin
- Participants
- 36 participants
- Comparison
- Extravascular ICD lead with left mid-axillary vs left pectoral PG
- Left mid-axillary PGn = 27
- Left pectoral PGn = 6
- Outcome
- Safety and feasibility: acute sensing and defibrillation testing
- Follow-up
- Acute
Methodological detailsnonrandomized, single-center, acute
- Nonrandomized
- Single-center
- Acute
Main finding
As reported in the abstract
Successful acute defibrillation using ≤35 J
| Group | Value | Defibrillation energy, mean ± SD |
|---|---|---|
| Left mid-axillary PG | 100% | 16.3±8.6 J |
| Left pectoral PG | 83% | 21.0±8.4 J |
Value
Left mid-axillary PG100%
Left pectoral PG83%
Defibrillation energy, mean ± SD
Left mid-axillary PG16.3±8.6 J
Left pectoral PG21.0±8.4 J
- All evaluable episodes automatically sensed, detected and shocked
- n=93
Further findings
- VF conversion with defibrillation energies ≥10 J below maximum device output (left mid-axillary PG)
- 89% · 24 of 27
- VF conversion with defibrillation energies ≥10 J below maximum device output (left mid-axillary PG): 24 of 27
Safety
- No serious device-related intraoperative adverse events observed
Original publication
Initial Experience With Intercostal Insertion of an Extravascular ICD Lead Compatible With Existing Pulse Generators. Circ Arrhythm Electrophysiol. Published 24 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →