Integration of Two-Dimensional Echocardiography: A Novel Risk Indicator for ST-Segment Elevation Myocardial Infarction
Authors' conclusion
The 2D echocardiographic diagnostic information based on cluster analysis had good prognostic value for STEMI population
Study context
- Population
- Patients with acute STEMI undergoing percutaneous coronary intervention (PCI), Yongchuan Hospital of Chongqing Medical University, January 2016–January 2019
- Participants
- 633 patients
- Exposure
- Echocardiographic cluster information added to clinical variables and left ventricular ejection fraction (LVEF) for mortality prediction
- Outcome
- All-cause mortality
- Follow-up
- 3-year follow-up
Methodological detailssingle-centre, cluster analysis, Free online calculator developed
- Single-centre
- Cluster analysis
- Free online calculator developed
Main finding
As reported in the abstract
Clinical variables
0.848
95% CI 0.809–0.888
AUC
Clinical variables + LVEF
0.872
95% CI 0.836–0.908
AUC
Clinical variables + LVEF + cluster information
0.906
95% CI 0.878–0.934
AUC
Each group vs clinical variablesAdjusted odds ratio (95% CI)P value
Cluster informationmultivariate; cluster independently associated with all-cause mortality
7.33(3.99–14.06)
P < 0.001- Clinical variables + LVEF + cluster information · further improvement
- AUC 0.906 (95% CI 0.878–0.934); P < 0.001
- All-cause mortality over 3-year follow-up
- 108 (17.1%)
Observational data: associations, not effects.
Further findings
- Statistically significant differences in most clinical variables, echocardiography and survival outcomes between clusters
Original publication
Integration of Two-Dimensional Echocardiography: A Novel Risk Indicator for ST-Segment Elevation Myocardial Infarction. ESC Heart Fail. Published 1 July 2024. doi:10. 1002/ ehf2. 14939
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