Heart failure & cardiomyopathies
International validation of the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score in heart failure
Authors' conclusion
In patients diagnosed with HFrEF, the power of the MECKI score was confirmed in terms of prognosis and risk stratification
Study context
- Population
- Patients with HF with reduced ejection fraction (HFrEF) at international (non-Italian) centres, followed up 1998–2019
- Participants
- 1,042 patients · 8 international centres
- Comparison
- MECKI score <10% vs 10-20% vs ≥20%
- Outcome
- Event-free survival
Methodological detailsretrospective multicentre cohort, international (8 centres: 7 European, 1 Asian)
- Retrospective multicentre cohort
- International (8 centres: 7 European, 1 Asian)
Performance
As reported in the abstract
Median event-free survival
P < 0.0001
Further findings
- ROC curves and AUC similar to those of the original internal validation studies
Original publication
International validation of the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score in heart failure. Eur J Prev Cardiol. Published 8 June 2023. doi:10. 1093/ eurjpc/ zwad191
Summarised from the published abstract; every number is checked against it