Heart failure & cardiomyopathies

International validation of the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score in heart failure

Eur J Prev CardiolPublished External validation study of a prognostic score

Authors' conclusion

In patients diagnosed with HFrEF, the power of the MECKI score was confirmed in terms of prognosis and risk stratification

Study context

Population
Patients with HF with reduced ejection fraction (HFrEF) at international (non-Italian) centres, followed up 1998–2019
Participants
1,042 patients · 8 international centres
Comparison
MECKI score <10% vs 10-20% vs ≥20%
Outcome
Event-free survival
Methodological detailsretrospective multicentre cohort, international (8 centres: 7 European, 1 Asian)
  • Retrospective multicentre cohort
  • International (8 centres: 7 European, 1 Asian)

Performance

As reported in the abstract

Median event-free survival

P < 0.0001

Further findings

ROC curves and AUC similar to those of the original internal validation studies

Original publication

International validation of the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score in heart failure. Eur J Prev Cardiol. Published 8 June 2023. doi:10.1093/eurjpc/zwad191

Summarised from the published abstract; every number is checked against it

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