Coronary disease & ACS

Intraventricular conduction delays as a predictor of mortality in acute coronary syndromes

Eur Heart J Acute Cardiovasc CarePublished Retrospective registry analysis

Authors' conclusion

RBBB, LBBB, and NIVCD were associated with higher cardiac mortality in ACS patients.

Study context

Population
Consecutive acute coronary syndrome (ACS) patients undergoing coronary angiography with an electrocardiographic (ECG) available, 2007–18; mean age 68.3 years3,156 died
Participants
9,749 patients
Exposure
Intraventricular conduction delays (IVCD) vs no IVCD
Outcome
Cardiac mortality
Follow-up
Median 6.1 years
Methodological detailsconsecutive patients, competing-risk analysis, Mortality and cause-of-death data from the Finnish national register, no losses to follow-up (until 31 December 2020)
  • Consecutive patients
  • Competing-risk analysis
  • Mortality and cause-of-death data from the Finnish national register, no losses to follow-up (until 31 December 2020)

Main finding

As reported in the abstract

SDH

1.37

CI 1.15–1.64P < 0.0001

Right bundle branch block (RBBB)

SDH

1.63

CI 1.31–2.03P < 0.0001

Left bundle branch block (LBBB)

SDH

2.68

CI 2.19–3.27

NIVCD

Observational data: associations, not effects.

Further findings

Cardiac mortality, additionally adjusted for LVEF

RBBB and NIVCD remained significant risk factors

Original publication

Intraventricular conduction delays as a predictor of mortality in acute coronary syndromes. Eur Heart J Acute Cardiovasc Care. Published 29 March 2023. doi:10.1093/ehjacc/zuad031

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