Intraventricular conduction delays as a predictor of mortality in acute coronary syndromes
Authors' conclusion
RBBB, LBBB, and NIVCD were associated with higher cardiac mortality in ACS patients.
Study context
- Population
- Consecutive acute coronary syndrome (ACS) patients undergoing coronary angiography with an electrocardiographic (ECG) available, 2007–18; mean age 68.3 years3,156 died
- Participants
- 9,749 patients
- Exposure
- Intraventricular conduction delays (IVCD) vs no IVCD
- Outcome
- Cardiac mortality
- Follow-up
- Median 6.1 years
Methodological detailsconsecutive patients, competing-risk analysis, Mortality and cause-of-death data from the Finnish national register, no losses to follow-up (until 31 December 2020)
- Consecutive patients
- Competing-risk analysis
- Mortality and cause-of-death data from the Finnish national register, no losses to follow-up (until 31 December 2020)
Main finding
As reported in the abstract
SDH
1.37
CI 1.15–1.64P < 0.0001
Right bundle branch block (RBBB)
SDH
1.63
CI 1.31–2.03P < 0.0001
Left bundle branch block (LBBB)
SDH
2.68
CI 2.19–3.27
NIVCD
Observational data: associations, not effects.
Further findings
Cardiac mortality, additionally adjusted for LVEF
- RBBB and NIVCD remained significant risk factors
Original publication
Intraventricular conduction delays as a predictor of mortality in acute coronary syndromes. Eur Heart J Acute Cardiovasc Care. Published 29 March 2023. doi:10. 1093/ ehjacc/ zuad031
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