Arrhythmias & electrophysiology
Lead performance of stylet-driven leads in left bundle branch area pacing: Results from a large single-center cohort and insights from in vitro bench testing
Authors' conclusion
The incidence of early conductor failure in LBBAP seems higher than with conventional RVp sites. The most vulnerable lead part seems to be the interelectrode space between the tip housing and ring electrode. Excessive angulation and preconditioning might contribute to early fatigue fracture.
Study context
- Population
- Adult patients with left bundle branch area pacing (LBBAP) using stylet-driven pacing leads
- Participants
- 325 vs 149
- Exposure
- LBBAP vs conventional RV apical pacing
- LBBAPn = 325
- RVpn = 149reference
- Outcome
- Lead fracture rates of stylet-driven leads
- Follow-up
- Median 18 months
Methodological detailssingle-centre, in vitro bench testing
- Single-centre
- In vitro bench testing
Main finding
As reported in the abstract
Conductor fracture between tip housing and ring electrode
LBBAP: conductor fracture between tip housing and ring electrode
2 patients
0.6%
Observational data: associations, not effects.
Further findings
High lead bending angulations on X-ray analysis
- High lead bending angulations (X-ray analysis)
- 1.3%
Early conductor fracture in accelerated bench testing
- Higher probability of early conductor fracture with excessive vs standard preconditioned leads
- In vitro bench testing
Original publication
Lead performance of stylet-driven leads in left bundle branch area pacing: Results from a large single-center cohort and insights from in vitro bench testing. Heart Rhythm. Published 1 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →