Heart failure & cardiomyopathies
Left Bundle Branch Area Pacing in Patients With Cardiac Sarcoidosis
Authors' conclusion
LBBAP in CS is feasible and provided stable long-term lead performance in this cohort.
Study context
- Population
- Patients with cardiac sarcoidosis (Heart Rhythm Society criteria) undergoing left bundle branch area pacing (LBBAP), January 2020 to March 2024
- Participants
- 19 patients
- Outcome
- Procedural success, lead performance and outcomes of LBBAP
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Baseline paced QRS duration, mean
139 ± 25 milliseconds
Threshold, mean
0.75 ± 0.26 V
R-wave amplitude
15.2 ± 6.3 mV
Impedance
738 ± 208 Ω
Observational data: associations, not effects.
Further findings
Left ventricular ejection fraction (LVEF) in patients with LBBB, QRS >130 ms and LVEF <50% (n = 4)
- LVEF improved from baseline to follow-up
- 27% ± 17% to 50% ± 12% (P = 0.06)
Pacing parameters by septal involvement
- No differences in pacing parameters based on septal involvement
Safety
Acute procedural complications
- No acute complications
Original publication
Left Bundle Branch Area Pacing in Patients With Cardiac Sarcoidosis. JACC Clin Electrophysiol. Published 20 November 2025. doi:10. 1016/ j. jacep. 2025. 09. 046
Composed by AI from the published abstract and checked against it. How Briefs are made →