Heart failure & cardiomyopathies
Left ventricular functional recovery after atrial fibrillation catheter ablation in heart failure: a prediction model
Authors' conclusion
In this multi-centre study, a simple four-parameter score predicted LVEF recovery after AF ablation in patients with HF and discriminated clinical outcomes.
Study context
- Population
- Patients with heart failure (HF) and impaired left ventricular ejection fraction (LVEF) (<50%) undergoing atrial fibrillation (AF) ablation
- Participants
- 605 patients8 European centres
- Exposure
- Antwerp score for prediction of LVEF recovery after AF ablation
- Respondersn = 427
- Outcome
- LVEF recovery (2021 Universal Definition of HF criteria)
- Follow-up
- 12 months
Methodological detailsexternal validation of a prediction model, multicentre, 8 European centres, retrospectively identified
- External validation of a prediction model
- Multicentre
- 8 European centres
- Retrospectively identified
Main finding
As reported in the abstract
Prediction of LVEF recovery (external validation of the Antwerp score)
- AUC
- 0.86 [95% CI 0.82-0.89], P < .001
- Hosmer-Lemeshow
- P = .29
- Probability of LVEF recovery, score < 2
- 93%
- Probability of LVEF recovery, score > 3
- 24%
Observational data: associations, not effects.
Further findings
Clinical outcomes, responders vs non-responders
| OR (95% CI) | P value | ||
|---|---|---|---|
| RespondersPositive ventricular remodelling | 8.91 (4.45–17.84) | P < 0.001 | |
| RespondersHF hospitalizations | 0.09 (0.05–0.18) | P < 0.001 | |
| RespondersMortality | 0.11 (0.04–0.31) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Left ventricular functional recovery after atrial fibrillation catheter ablation in heart failure: a prediction model. Eur Heart J. Published 30 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →