Valvular & structural heart disease
Left ventricular mechanical dispersion as a predictor of the need for pacemaker implantation after transcatheter aortic valve implantation: MeDiPace transcatheter aortic valve implantation (TAVI) study
Main finding · MeDiResult — go to the resultOdds ratio 1.73 95% CI 1.22–2.45Authors' conclusion
MeDi may be used as an echocardiographic functional predictor of the need for PM after TAVI.
Study context
- Population
- Consecutive patients undergoing TAVI; mean age 80 years, 44% women
- Participants
- 200 patients
- Exposure
- Pacemaker (PM) vs no PM after TAVI
- PMn = 29
- Outcome
- Need for permanent PM implantation after TAVI, predicted by LV mechanical dispersion (MeDi) on speckle tracking echocardiography
- Follow-up
- 3 months after TAVI
Methodological detailsconsecutive enrolment
- Consecutive enrolment
Main finding
MeDi
Odds ratio
1.73
95% CI 1.22–2.45
By group
MeDi
OR 1.73 (95% CI 1.22–2.45)
As reported in the abstract
Observational data: associations, not effects.
Further findings
RBBB as predictor of PM need
| OR (95% CI) | ||
|---|---|---|
| RBBBIndependent predictor | 8.98 (1.78–45.03) | |
| 0.050.21520Odds ratio (log scale) |
Incremental value of mechanical dispersion (MeDi) added to RBBB
- AUC with MeDi added to RBBB
- 0.73
- P = 0.01
QRS duration, RBBB, first-degree atrioventricular (AV) block
- Significantly different between PM and no PM
Original publication
Left ventricular mechanical dispersion as a predictor of the need for pacemaker implantation after transcatheter aortic valve implantation: MeDiPace TAVI study. Eur Heart J Cardiovasc Imaging. Published 17 November 2023. doi:10.
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