Valvular & structural heart disease
Long-term outcomes of measured and predicted prosthesis-patient mismatch following transcatheter aortic valve replacement
Main finding · 10-year all-cause mortalityResult — go to the resultAdjusted hazard ratio 0.73 95% CI 0.55–0.96Authors' conclusion
We observed no increased risk of death in patients with PPM over a median follow-up time of 429 days.
Study context
- Population
- Patients undergoing transcatheter aortic valve replacement (TAVR) in a prospective registry
- Participants
- 2,463 patients
- Exposure
- Prosthesis-patient mismatch (PPM) vs no PPM, by measured or predicted EOAi
- Outcome
- All-cause mortality
- Follow-up
- 10 years (median 429 days)
Main finding
10-year all-cause mortality · median follow-up 429 days
Adjusted hazard ratio
0.73
95% CI 0.55–0.96
Predicted PPMTHV vs No PPM
adjusted HR 0.73 (95% CI 0.55–0.96)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Measured PPM | Predicted PPMTHV | Predicted PPMCT | No PPM | |
|---|---|---|---|---|---|
| Frequency of PPM by definition | |||||
| Moderate | 27.0% | 11.3% | 12.0% | Not reported in the abstract | No PPM: not reported in the abstract |
| Severe | 8.7% | 1.2% | 0.1% | Not reported in the abstract | No PPM: not reported in the abstract |
Original publication
Long-term outcomes of measured and predicted prosthesis-patient mismatch following transcatheter aortic valve replacement. EuroIntervention. Published 17 November 2023. doi:10.
Summarised from the published abstract; every number is checked against it