Arrhythmias & electrophysiology
Lesion area, ablation time, fluoroscopic time, and short-term outcomes among 3 pulsed field ablation systems
Authors' conclusion
Despite similar total lesion areas, the PFA systems showed distinct lesion patterns. FP had the shortest procedure time, VP the lowest radiation exposure, and PS the least haptoglobin reduction, potentially indicating less hemolysis.
Study context
- Population
- Patients with atrial fibrillation (paroxysmal and persistent) undergoing pulsed field ablationparoxysmal: 54, persistent: 21 · paroxysmal 54 · persistent 21
- Participants
- 75 patients
- Comparison
- Pulsed field ablation (PFA)-related features among the FP, VP, and PS systems
- FPn = 25
- VPn = 25
- PSn = 25
- Outcome
- PV isolation time
Main finding
As reported in the abstract
FP vs VP: P < 0.0003 · FP vs PS: P < 0.0003
Further findings
Fluoroscopy time — VP vs FP · lower with VP
P < 0.0003
| Outcome | FP | VP | PS | P value |
|---|---|---|---|---|
| Fluoroscopy timeVP vs PS · lower with VP | P < 0.0003 | |||
| Haptoglobin declinePS vs FP · smallest with PS | 35 (range 24–46) | 36 (range 11–52) | 8 (range 0–17) mg/dL | P < 0.0003 |
| Haptoglobin declinePS vs VP · smallest with PS | P < 0.0003 |
Lesion distribution
- FP created larger lesions for the posterior right inferior pulmonary vein (PV)
- VP created broader lesions for the posterior left inferior PV (LIPV) and smaller for the posterior right superior PV (RSPV) and right inferior PV
- PS created greater lesions for the posterior right superior PV and smaller for the anterior left superior PV
Original publication
Lesion area, ablation time, fluoroscopic time, and short-term outcomes among 3 pulsed field ablation systems. Heart Rhythm. Published 5 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →