Arrhythmias & electrophysiology
Comparative evaluation of 2 pulsed field ablation systems for atrial fibrillation: insights from real-world clinical implementation and short-term outcomes
Authors' conclusion
Both PFA systems could be safely and rapidly implemented into clinical practice of an experienced center.
Study context
- Population
- Patients undergoing pulsed field ablation (PFA) catheter ablation of AF (mostly paroxysmal, nearly one-third persistent)first 40 consecutive per system
- Participants
- 40 vs 40
- Exposure
- Pentaspline PFA catheter vs circular PFA catheter
- Circular cathetern = 40
- Pentaspline cathetern = 40
- Outcome
- Procedural parameters
Methodological detailsconsecutive patients, single-centre
- Consecutive patients
- Single-centre
Main finding
As reported in the abstract
| Group | Procedure duration | Left atrial (LA) dwell time | Fluoroscopy duration |
|---|---|---|---|
| Circular catheter | 42.0 minutes | 29.0 minutes | 13.2 min |
| Pentaspline catheter | 43.0 minutes | 31.0 minutes | 11.9 minutes |
Procedure duration
Circular catheter42.0 minutes
Pentaspline catheter43.0 minutes
Left atrial (LA) dwell time
Circular catheter29.0 minutes
Pentaspline catheter31.0 minutes
Fluoroscopy duration
Circular catheter13.2 min
Pentaspline catheter11.9 minutes
- Circular catheter vs Pentaspline catheter: P = 0.292 — procedure duration
- Circular catheter vs Pentaspline catheter: P = 0.623 — LA dwell time
- Circular catheter vs Pentaspline catheter: P = 0.132 — fluoroscopy duration
Observational data: associations, not effects.
Further findings
- Pentaspline catheter: no learning curve in procedural parameters over 40 procedures
- Circular catheter: significant decrease in LA dwell time and fluoroscopy duration, first vs last 10 procedures
Safety
Overall procedural complications
P = 0.71
Minor complications
P = 1.00
Original publication
Comparative evaluation of 2 pulsed field ablation systems for atrial fibrillation: insights from real-world clinical implementation and short-term outcomes. Heart Rhythm. Published 7 November 2024. doi:10.
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