Heart failure & cardiomyopathies

Long-Term Exposure to Road Traffic Noise and Incident Heart Failure: Evidence From UK Biobank

JACC Heart FailPublished Prospective cohort study

Study context

Population
Participants without heart failure (HF) at baseline in UK Biobank12,817 incident HF
Participants
424,767 participants
Exposure
Higher vs lower long-term residential road traffic noise exposure
Outcome
Incident HF
Follow-up
Median 12.5 years
Methodological detailsUK Biobank
  • UK Biobank

Main finding

As reported in the abstract

median 12.5 years
Hazard ratio (95% CI)
Per 10 dB[A] increase in Lden
1.08(1.00–1.16)
Lden >65 dB[A]vs Lden ≤55 dB[A]
1.15(1.02–1.31)

Observational data: associations, not effects.

Further findings

Combined road traffic noise and air pollution (fine particles, nitrogen dioxide)

Strongest combined effects with high exposure to both road traffic noise and air pollution

Mediation by prior acute myocardial infarction (AMI) before HF within 2 years

Proportion of noise–HF association mediated by prior AMI
12.5%
  • Time-dependent mediation

Original publication

Long-Term Exposure to Road Traffic Noise and Incident Heart Failure: Evidence From UK Biobank. JACC Heart Fail. Published 24 May 2023. doi:10.1016/j.jchf.2023.04.003

Composed by AI from the published abstract and checked against it. How Briefs are made →

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