Heart failure & cardiomyopathies
Risk of Adverse Outcomes Associated With Cardiac Sarcoidosis Diagnostic Schemes
Authors' conclusion
CS patients who met the 1993 and the 2006 criteria had higher odds of adverse clinical outcomes.
Study context
- Population
- Cardiac sarcoidosis (CS) patients, Cardiac Sarcoidosis Consortium international registry
- Participants
- 310 / 312 / 480 / 112
- Exposure
- Patients meeting vs not meeting each CS diagnostic scheme
- 1993 Japanesen = 310
- 2006 Japanesen = 312
- 2014 Heart Rhythm Societyn = 480
- 2017 Japanesen = 112
- Outcome
- Adverse outcome event: all-cause mortality, LV assist device placement, heart transplantation or appropriate ICD therapy
Methodological detailsinternational registry
- International registry
Main finding
As reported in the abstract
Adverse outcome event, met vs did not meet each scheme
Odds ratio (95% CI)P value
1993 Japanesevs Did not meet 1993 criteria
2.00(1.38–2.90)
P < 0.0012006 Japanesevs Did not meet 2006 criteria
2.54(1.74–3.71)
P < 0.0012014 Heart Rhythm Societyvs Did not meet 2014 criteria
1.39(0.85–2.27)
P = 0.182017 Japanesevs Did not meet 2017 criteria
1.51(0.97–2.33)
P = 0.067Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Risk of Adverse Outcomes Associated With Cardiac Sarcoidosis Diagnostic Schemes. JACC Clin Electrophysiol. Published 24 May 2023. doi:10.
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