Heart failure & cardiomyopathies
Long-term outcomes in nonprogressors to cardiac resynchronization therapy
Authors' conclusion
Nonprogressors to CRT have superior medium-term outcomes but similar long-term outcomes to progressors and inferior outcomes to responders and super-responders.
Study context
- Population
- HF patients with Left Ventricular Ejection Fraction (LVEF) ≤35% and QRS ≥120 ms undergoing Cardiac Resynchronization Therapy (CRT) at Cleveland Clinic, Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center, 2003–2014
- Participants
- 1,058 patients
- Exposure
- CRT response categories by LVEF change
- Outcome
- Survival free of LVAD implantation and heart transplantation
- Follow-up
- Mean 8.7 ± 5.4 years
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Survival free of LVAD and heart transplant · 4 years and 8.7 ± 5.4 years
- Differed significantly between response groups at 4 years and long term; super-responders best, progressors worst
- P < .001
Observational data: associations, not effects.
Original publication
Long-term outcomes in nonprogressors to cardiac resynchronization therapy. Heart Rhythm. Published 7 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →