Arrhythmias & electrophysiology
Long-term outcomes of catheter ablation compared with medical therapy in atrial fibrillation
Authors' conclusion
In this cohort study, patients who received CA demonstrated a reduction in the risk of long-term adverse cardiovascular outcomes compared with medical therapy in patients with AF, providing some data to indicate the effects of CA in the long-term.
Study context
- Population
- Patients with atrial fibrillation (AF) as primary diagnosis (hospitalisation, ED or physician visit), Alberta administrative data, October 1, 2008 – March 31, 2018
- Participants
- 39,966 patients
- Exposure
- Catheter ablation vs rate control or rhythm control with medication
- Catheter ablation (CA)n = 2,077reference
- Rate controln = 29,467
- Rhythm control with medicationn = 8,422
- Outcome
- Composite of:
- All-cause death
- Hospitalisation for HF
- Stroke
- Follow-up
- Median 6.3 years
Methodological detailspopulation-based
- Population-based
Main finding
As reported in the abstract
CA
4.0/100 person-years
Rate control
8.7/100 person-years
Rhythm control with medication
6.8/100 person-years
Each group vs CAHazard ratio (95% CI)
Rate control
1.28(1.09–1.50)
Rhythm control with medication
1.21(1.03–1.43)
Observational data: associations, not effects.
Original publication
Long-term outcomes of catheter ablation compared with medical therapy in atrial fibrillation. Heart Rhythm. Published 6 December 2024. doi:10.
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