Heart failure & cardiomyopathies
MELD Score Predicts Outcomes in Patients with Advanced Heart Failure: A Longitudinal Evaluation
Main finding · Combined outcome (death, urgent transplant, LVAD)Result — go to the resultHazard ratio 1.094 95% CI 1.003–1.196Authors' conclusion
The MELD score and its longitudinal changes are effective predictors of adverse outcomes in AHF.
Study context
- Population
- Patients with advanced HF on maximum tolerated guideline medical therapy
- Participants
- 162 patients
- Exposure
- MELD score vs MELD-Na, MELD-XI, MAGGIC risk score and MECKI for prognosis
- Outcome
- Composite of:
- Death
- Urgent heart transplant
- LVAD implant
- Follow-up
- 31.4 ± 15.6 months
Methodological detailslongitudinal
- Longitudinal
Main finding
As reported in the abstract
Combined outcome:
- Death
- Urgent transplant
- LVAD
Hazard ratio
1.094
95% CI 1.003–1.196
By group
MELD
0.887
AUC
MELD
HR 1.094 (95% CI 1.003–1.196)
Per unit increase in MELD, as printed
Observational data: associations, not effects.
Further findings
Clinical correlates of MELD score (multiple regression)
- NT-proBNP (positive correlation), β = 0.215
- P = 0.041
- Furosemide dosage (positive correlation), β = 0.187
- P = 0.040
- TAPSE (negative correlation), β = −0.204
- P = 0.047
Original publication
MELD Score Predicts Outcomes in Patients with Advanced Heart Failure: A Longitudinal Evaluation. ESC Heart Fail. Published 7 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →