Arrhythmias & electrophysiology
Minimally invasive epicardial surgical left atrial appendage exclusion for atrial fibrillation patients at high risk for stroke and for bleeding
Main finding · Thromboembolic eventsResult — go to the resultAdjusted hazard ratio 0.672 95% CI 0.394–1.146Authors' conclusion
In AF patients not taking oral anticoagulation who are at high risk for stroke and for bleeding, minimally invasive, thoracoscopic, epicardial LAAE was associated with a lower rate of thromboembolic events.
Study context
- Population
- Atrial fibrillation (AF) patients at high risk for stroke and bleeding, not receiving OAC at baseline or follow-upmatched cohort
- Participants
- 243 vs 972
- Exposure
- Epicardial left atrial appendage exclusion (LAAE) vs no LAAE
- LAAEn = 243
- Controln = 972reference
- Outcome
- Thromboembolic events
- Follow-up
- 1 year
Methodological detailspropensity-score matched (1:4), Medicare claims data
- Propensity-score matched (1:4)
- Medicare claims data
Main finding
As reported in the abstract
Adjusted hazard ratio
0.672
95% CI 0.394–1.146
By group
LAAEvs Control
adjusted HR 0.672 (95% CI 0.394–1.146)
- Absolute risk reduction 4.8% (95% CI 0.6%-8.9%)
- P = 0.028
Observational data: associations, not effects.
Original publication
Minimally invasive epicardial surgical left atrial appendage exclusion for atrial fibrillation patients at high risk for stroke and for bleeding. Heart Rhythm. Published 29 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →