Acute cardiac care & resuscitation
Mitral valve prolapse in sudden cardiac arrest survivors: Coincidence or causal relationship?
Authors' conclusion
Echocardiographic findings such as mitral annular disjunction, SADN, Pickelhaube sign, and increased segmental strain may be useful in the assessment of the relation between SCA and MVP. Malignant arrhythmias often recur in SCA survivors with iMVP.
Study context
- Population
- Patients with mitral valve prolapse (MVP) who experienced sudden cardiac arrest (SCA), treated at one centre, 2009–202475 SCA survivors with MVP
- Participants
- 28 / 14 / 112
- Exposure
- SCA survivors with isolated MVP (iMVP) vs SCA survivors with non-iMVP without other defined structural heart disease vs MVP controls without SCA
- iMVPn = 28
- non-iMVPn = 14reference
- Controln = 112
- Outcome
- Echocardiographic and ECG findings
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Higher absolute longitudinal strain in basal and mid inferior and inferolateral segments with iMVP
- Differences also observed vs control group
- iMVP vs non-iMVP: P = 0.006
- iMVP vs non-iMVP: P = 0.008
- iMVP vs non-iMVP: P = 0.001
Observational data: associations, not effects.
Further findings
| Outcome | iMVP | non-iMVP |
|---|---|---|
| Cumulative incidence of appropriate ICD shocks · 6 years | 62% | 23% |
Original publication
Mitral valve prolapse in sudden cardiac arrest survivors: Coincidence or causal relationship? Heart Rhythm. Published 7 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →