Arrhythmias & electrophysiology
Mode and Characteristics of Arrhythmia Initiation in Idiopathic Ventricular Fibrillation: A THESIS Substudy
Authors' conclusion
Pause-dependent initiation occurred in more than a quarter of arrhythmic episodes in IVF patients. PVCs having long (between 350 and 500 ms) and very long (>500 ms) coupling intervals were observed at the initiation of nearly a quarter of PVT episodes.
Study context
- Population
- Patients with short or long-coupled polymorphic ventricular tachycardia (PVT)/idiopathic VF (idiopathic ventricular fibrillation (IVF)) in THESIS
- Participants
- 180 patients410 PVT episodes
- Outcome
- Incidence of pause-dependent arrhythmia initiation (prolongation by >20 ms of the preceding cycle length)
Main finding
As reported in the abstract
Pause-dependent initiation, overall
109 of 401
27.2%
Pause-dependent during baseline supraventricular rhythm without premature ventricular complexes (PVCs)
45
15.6%
Pause-dependent during baseline rhythm including PVCs
64
60.4%
Observational data: associations, not effects.
Further findings
Baseline rhythm at arrhythmia onset
- Supraventricular rhythm without ambient PVCs
- 295; 72%
- Baseline rhythm including PVCs
- 106 (25.9%)
Multiple initiation types (patients with ≥4 events)
- More than one type of initiation (mean 2.6 types)
- 94.4%
Coupling interval of initiating PVCs
- <350 ms
- 76.6%
- 350-500 ms
- 20.72%
- >500 ms
- 2.7%
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →