Multivariate Linear Regression to Predict Association of Non-Invasive Arterial Stiffness with Cardiovascular Events
Authors' conclusion
PWV was found to be associated with CVD and its related risk factors such as diabetes, obesity and hypertension.
Study context
- Population
- Participants randomly selected from the Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort study (9704 participants)
- Participants
- 363 / 226 / 292
- Exposure
- Arterial stiffness parameters in cardiovascular disease (CVD) event vs normal vs healthy participants
- Healthyn = 363reference
- Normaln = 226
- Eventn = 292
- Outcome
- Association of non-invasive arterial stiffness parameters (PWV, cardio-ankle vascular index (CAVI), central aortic pressure (CAP), CAI) with CVD
Methodological detailsnested in MASHAD cohort, multivariate multiple regression
- Nested in MASHAD cohort
- Multivariate multiple regression
Main finding
As reported in the abstract
PWV and CVD group
- Mean pulse wave velocity (PWV) significantly higher in patients with confirmed CVD event
- P < 0.001
- Significant association between PWV and CVD group (normal vs healthy and event vs healthy), adjusted
- P < 0.05
Observational data: associations, not effects.
Further findings
Risk factors and arterial stiffness
- Hypertension and obesity associated with PWV; diabetes associated with central augmentation index (CAI)
- P < 0.05
Original publication
Multivariate Linear Regression to Predict Association of Non-Invasive Arterial Stiffness with Cardiovascular Events. ESC Heart Fail. Published 25 November 2024. doi:10.
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