Heart failure & cardiomyopathies
New insight: Particle Flow Rate from the Airways as an Indicator of Cardiac Failure in the Intensive Care Unit
Authors' conclusion
Patients with post-operative cardiac failure following cardiac surgery exhibited an increase in exhaled particle mass and PFR compared with the control group, indicating a significant difference between those two groups.
Study context
- Population
- Mechanically ventilated ICU patients after cardiac surgery
- Participants
- 20 participants
- Comparison
- Post-operative cardiac failure vs no cardiac failure after cardiac surgery
- Cardiac failuren = 10
- Controln = 10reference
- Outcome
- Particle flow rate (PFR) in exhaled air (particles 0.41-4.55 μm, PExA device)
Main finding
As reported in the abstract
PFR
P < 0.001
Observational data: associations, not effects.
Further findings
Particle mass
P = 0.002
Total time in mechanical ventilation
P < 0.001
ICU length of stay
P = 0.007
| Outcome | Cardiac failure | Control | P value |
|---|---|---|---|
| Pre-operative LVEF | ≤40% | ≥50% | P < 0.001 |
Original publication
New insight: Particle Flow Rate from the Airways as an Indicator of Cardiac Failure in the Intensive Care Unit. ESC Heart Fail. Published 28 November 2022. doi:10. 1002/ ehf2. 14242
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