Heart failure & cardiomyopathies

New insight: Particle Flow Rate from the Airways as an Indicator of Cardiac Failure in the Intensive Care Unit

ESC Heart FailPublished Case-control study

Authors' conclusion

Patients with post-operative cardiac failure following cardiac surgery exhibited an increase in exhaled particle mass and PFR compared with the control group, indicating a significant difference between those two groups.

Study context

Population
Mechanically ventilated ICU patients after cardiac surgery
Participants
20 participants
Comparison
Post-operative cardiac failure vs no cardiac failure after cardiac surgery
  • Cardiac failuren = 10
  • Controln = 10reference
Outcome
Particle flow rate (PFR) in exhaled air (particles 0.41-4.55 μm, PExA device)

Main finding

As reported in the abstract

PFR

P < 0.001

Observational data: associations, not effects.

Further findings

Particle mass

P = 0.002

Total time in mechanical ventilation

P < 0.001

ICU length of stay

P = 0.007

OutcomeCardiac failureControlP value
Pre-operative LVEF≤40%≥50%P < 0.001

Original publication

New insight: Particle Flow Rate from the Airways as an Indicator of Cardiac Failure in the Intensive Care Unit. ESC Heart Fail. Published 28 November 2022. doi:10.1002/ehf2.14242

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